Friday, October 8, 2010

11:30 am - 02:00 pm: Registration, poster setup and lunch buffet

02:00 pm - 02:30 pm: Introductions (Marlene Belfort and David Shub)

Session I: Big RNAs (Chairperson: Scott Tenenbaum)

02:30 pm - 03:30 pm: Lynne Maquat (Keynote Talk)

mRNP Rearrangements During the Pioneer Round of Translation, Nonsense- Mediated mRNA Decay, and Thereafter

03:30 pm - 03:50 pm: Roopa Thapar

ERI mediated decay (EMD): Novel exonucleases and pathways in mRNA decay

03:50 pm - 04:10 pm: William Bauer

Structural comparison of pseudouridine-modified U2 snRNA/branchpoint site containing RNA duplexes

04:10 pm - 04:30 pm: Leonard Lipovich

Genome-wide computational and experimental analysis of long non- coding RNA genes in a complex human brain disorder

04:30 pm - 05:30 pm: Poster session 1 + Wine and cheese

05:30 pm - 07:00 pm: Dinner and room check-in

Session II: Aptamers, Ribozymes and RNAs (Chairperson: Tom Eickbush )

07:00 pm - 07:20 pm: Daiying Xu

Two classes of RNA aptamers as antagonists of human estrogen receptor alpha

07:20 pm - 07:40 pm: Elisa Biondi

A double-site acting kinase ribozyme

07:40 pm - 08:00 pm: Toby Soper

Positive regulation of RpoS by small RNAs and the role of Hfq

08:00 pm - 09:00 pm: Larry Gold (Keynote Talk)

SOMAmers: Proteomics to lung cancer to a Wellness Chip

09:00 pm - 10:00 pm: Social hour


Saturday, October 9, 2010

07:30 am - 08:30 am: Breakfast

Session III: RNA Folding and Assembly (Chairperson: Yi-Tao Yu )

08:30 am - 08:50 am: Joerg Schlatterer

Mapping the competing barriers that define alternative RNA 9 folding pathways

08:50 am - 09:10 am: Steve Meisburger

Time-resolved SAXS reconstructions reveal a kinetic intermediate in RNA folding

09:10 am - 09:30 am: Nathan Napper

Alternative assembly pathways of ribosomal 30S subunits in thermophilic bacteria

09:30 am - 10:00 am: Rob Knight (Mini-keynote Talk)

Nucleotides that are essential but not conserved

10:00 am - 11:00 am: Poster session 2

Session IV: RNA Structure (Chairperson: Michael Zuker )

11:00 am - 11:20 am: Matthew Seetin

Automated RNA tertiary structure prediction

11:20 am - 11:40 am: Jerome Waldispuhl

RNAmutants: A computational framework to explore the mutational landscape of structural RNAs: theory and applications

11:40 am - 12:00 pm: Dan Fabris

Higher-order structure of RNA by MS-based approaches

12:00 pm - 01:00 pm: Anna M. Pyle (Keynote Talk)

The tertiary structure and folding pathways of group II introns: paradigms for the assembly of large, multidomain RNAs and RNPs

01:00 pm - 02:00pm: Lunch/departure